Brain based disorders

 

 

AUTISM

With the newest statistics placing the rates of Autism at an alarming 1 in 50 children, there is much confusion and debate about what it causing this massive epidemic. Unfortunately, there is no one cause, but a combination of causes all coming together to create a complicated disease process. First we look for signs of birth trauma like a c-section, vacuum extraction, cord around the neck or low amniotic fluid. Even a long stressful birth can be enough. We then typically look at the healthy gut bacteria and how it’s effected. If good bacteria is lacking, it causes an autoimmune reaction and hypersensitivity, or an allergic reaction to foods. These foods then drive the inflammation reaction further when eaten (which is why gluten and casein free diets came into favor). Finally, there is a large toxic load to identify- typically heavy metals-that are found in the system. Research shows, on a cellular level, there is a low level of antioxidants (especially Super Oxide Dimutase) which allows the toxic load to get

If all of these factors are looked at and addressed at the same time, it is possible to see marked improvements in function and behavior. While this is not a simple task, knowing all the key players by using functional testing is imperative to get children healed and well. Fortunately, if we can find the cause, these children stand a fighting chance of recovering their lives.

ALZHEIMER’S DISEASE

Alzheimer’s Disease is a chronic neurodegenerative condition that affects the brain and its ability to process memory. In the recent years of research there have been some significant advances to the treatment and handling of this difficult problem. While no complete fix exists, it is still a disease that with proper care can vastly improve a person’s quality of life.

There can be a variable rate of causes that contribute to the problem. Some factors are an increase in brain inflammation (most notably homocysteine) that has been consistently identified in the Alzheimer patient population. A decrease in circulation to the brain from atherosclerosis is also a common finding that can affect the way the tissue of the brain can function.

Of course there can be a hormonal imbalance or a brain neurotransmitter imbalance. Typically the neurotransmitter that is deficient in the memory loss is acetylcholine. All of the latest research points to metabolic imbalances, most notably that the brain of an Alzheimer patient can no longer utilize insulin to get sugar in the brain cells. Without fuel, oxygen and stimulation, the tissues can no longer function. Getting insulin sensitivity restored and focusing on increasing the uptake of oxygen, gives the brain tissues exactly what they need.

Using additional energy sources like ketones are invaluable in getting memory restoration and potentially even repairing some neurological damage. It is the reason why so many reports have focused on coconut oil as a medium of getting people well based on its chain of fatty acids. Newest research has shown that fatty acids need to be in certain ratios to one another in order to get the maximum neurological and brain function effects. The ratio that is typically found in fish oil is not the correct ratio. Also most fish oil, no matter how pure, can contain heavy metals like mercury.

Of course in the neurology side of things, there is nothing more important than getting the brain lobes communicating again. This is typically done through stimulation with low level light therapy and neurofeedback. This is also where mercury or metal poisons becomes a problem as it will interfere with the brain signaling process.

All of these problems will typically be involved on some level and can be tested for. It is important to evaluate all of them separately and treat them all individually. All this testing and treatment is available exclusively at Superior Health Solutions.

 

PARKINSON’S DISEASE

Parkinson’s disease has long been known to be a neurological disease that affects the production of the neurotransmitter dopamine in the brain. While it has long been established that this is a neurodegenerative disease, what does not get enough attention when a patient is being cared for is the metabolic side of Parkinson’s. This report takes a look at the major factors of what happens in the course of the evolution of Parkinson’s disease from a neurological and metabolic standpoint.

Using the current theory of Braak’s Hypothesis of Parkinson’s, it is stated that the first neurological signs of Parkinson’s is shown in the enteric nervous system; meaning that it originates in the stomach. The gut-brain neurological connection has long been identified as mainly cranial nerve ten, called the Vagus Nerve. The Vagus nerve is the major supplier of parasympathetic nerve activity to the body (more on that in a bit). Therefore, if there is a problem with the stomach, especially leaky gut syndrome, it will affect the enteric nervous system and start the chain reaction that can cause Parkinson’s.
The parasympathetic nervous system, or Autonomic Nervous System (ANS) is the part of the signal from your brain that promotes calm and balance. It takes care of all your automatic functions like heartbeat and breathing. It is where digestion, sleep and healing occur. Your sympathetic nervous system on the other hand speeds things up. It takes over when your body needs to handle stress or an activity. This is where motion occurs. For a Parkinson’s patient, the sympathetic nervous system becomes dominant and instead of the body being at rest, the nervous system keeps some muscle firing accidentally and that is what is seen in the manifestation of tremors. With that, the most accurate definition of a Parkinson’s tremor is what is called an Autonomic Neuropathy. Advanced computerized technology can detect autonomic function levels in a completely non-invasive way.

The chemical reaction of the body that allows the ANS to return to control is called methylation. While methylation has many important functions in the body, there are a few that are extremely important for Parkinson’s. If your methyl groups are depleted, your body will not be able to create normal protein synthesis. Tyrosine, the essential amino acid that your body uses to make dopamine, will not be synthesized. Therefore, the production of dopamine will be decreased. On top of that, the proteins will instead be made into homocysteine which is an inflammation marker proven time and time again to negatively affect brain function. However dopamine (or any neurotransmitter that is created) additionally needs to bind to a methyl group in order to activate itself for function. So as you can see, methyl groups play an enormous role in the activation and propagation of Parkinson’s, yet most patients never have this pathway tested to determine the amount of methyl groups that they have available. It has been recorded time and time again that Parkinson’s patients routinely have low methylation capabilities.

Newer research on chronic cellular inflammation has now identified Parkinson’s disease as being as a Mitochondrial Dysfunction disease, affected by the NO/ONOO cycle. Nitric oxide (NO) is a chemical found in cells that is caused by long term inflammatory cycles due to physical traumas, chemical toxins, infections and emotional traumas as well. NO over time will peroxynitrie (ONOO) and superoxide, which are nasty free radicals that damage your cells from the inside out. They specifically damage the mitochondria of the cell, leading the cell to not be able to create enough energy to function properly. An increase in these elements serves to stimulate the sympathetic nervous system, driving it to be incapable of healing and causing the involuntary movements of Parkinson’s. Over the course of time, this leads to neurodegeneration.

The increase production of NO is one of many reasons that leads to decrease in the production of glutathione. Glutathione, notoriously depleted in Parkinson’s patients, is the major antioxidant of the body and is responsible for protection of the cellular and tissue structures from free radical and toxic damage. Produced inside each cell, if glutathione begins to run deficient or it cannot keep up with the amount of free radical damage then the body systems run without protection. Glutathione reduction researched has been linked to many conditions, but perhaps none more so than Parkinson’s. Also, research has stated that an increase in glutathione production will show significant improvements in Parkinson’s symptoms.

When there is an abnormal NO/ONOO cycle and a depletion of Glutathione, eventually the cells and tissues of the body will begin to become inflamed. This intracellular inflammation will cause damage to cell membranes and tissues. This decreases further the amount of energy a cell can create, decreases the activity of neurotransmitters (like dopamine), causes hormonal issues, damages DNA and interrupts healthy cell division which the brain uses to keep its function at a high level. This tissue damage is readily testable through a simple urinalysis that tests for toxic aldehydes that will be released when there is free radical oxidation of tissue.

Whenever you are dealing with brain based issues, chemical toxins play a role in disrupting function. The biggest threat to a Parkinson’s patient is heavy metal poisoning. Due to exposure from environment or even internal exposure due to old damage silver dental fillings or root canals, heavy metals will be able to pass the blood brain barrier and imbed in the brain disrupting the conductivity from one lobe to another. Some metals will competitively bind to dopamine receptors and mimic that dopamine is being depleted despite the fact that it is not. Blood testing is not diagnostic for heavy metals, so if there was toxic overload it would still go undetected.

While all Parkinson’s patients do not follow an exact formula, there are metabolic and neurological trends that have been noted in the research and in clinical treatments over and over again. It cannot be stated strongly enough that all of these markers are vastly intertwined. Heavy metals are broken down in the system by glutathione and methyl groups. Increase in the NO/ONOO cycle causes a decrease in glutathione and an increase in cell damaged measured by aldehydes. This then causes an increase in the sympathetic nervous system. On and on, what we have is a negative loop cycle that keeps recreating itself.

While these are now commonly accepted issues facing the Parkinson’s patient, they are typically not issues that have been addressed or even tested for to begin with. Patient protocols that aim to work with patients metabolically and neurologically hold the key to provide as much remission of the disease as possible.